SEC FORM 3SEC Form 3
FORM 3UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
 
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1. Name and Address of Reporting Person*
Joshi Manher

(Last)(First)(Middle)
C/O RHYTHM PHARMACEUTICALS, INC.
222 BERKELEY STREET, 12TH FLOOR

(Street)
BOSTONMA02116

(City)(State)(Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
08/17/2026
3. Issuer Name and Ticker or Trading Symbol
RHYTHM PHARMACEUTICALS, INC. [ RYTM ]
Foreign Trading Symbol
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
checkbox checkedOfficer (give title below)Other (specify below)
Chief Medical Officer
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
checkbox checkedForm filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year)3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
Remarks:
Exhibit 24 - Power of Attorney
No securities are beneficially owned.
/s/ Stephen Vander Stoep, attorney-in-fact for Manher Joshi08/18/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
							EXHIBIT 24
				POWER OF ATTORNEY

       KNOW ALL BY THESE PRESENTS, that the undersigned hereby constitutes and
appoints each of David Meeker, M.D., Jim Flaherty, Christopher German and
Stephen Vander Stoep signing singly, as his true and lawful attorney-in-fact to:

       (1)   execute for and on behalf of the undersigned, in the undersigned?s
 capacity as an officer of Rhythm Pharmaceuticals, Inc. (the ?Company?), Forms
 3, 4, and 5 in accordance with Section 16(a) of the Securities Exchange Act of
 1934 and the rules thereunder and any other forms or reports the undersigned
 may be required to file in connection with the undersigned?s ownership,
acquisition, or disposition of securities of the Company;

       (2)   do and perform any and all acts for and on behalf of the
undersigned which may be necessary or desirable to complete and execute any
such Form 3, 4, or 5, or other form or report, and timely file such form or
report with the U.S. Securities and Exchange Commission and any stock exchange
 or similar authority; and

       (3)   take any other action of any type whatsoever in connection with
the  foregoing which, in the opinion of such attorney-in-fact, may be of
benefit to, in the best interest of, or legally required by, the undersigned,
 it being understood that the documents executed by such attorney-in-fact on
 behalf of the undersigned, pursuant to this Power of Attorney, shall be in
such form and shall  contain such terms and conditions as such
attorney-in-fact may approve in his discretion.

       The undersigned hereby grants to each such attorney-in-fact full power
 and authority to do and perform each and every act and thing whatsoever
requisite, necessary, and proper to be done in the exercise of any of the
rights and powers herein granted, as fully to all intents and purposes as the
 undersigned might or could do if personally present, with full power of
substitution or revocation, hereby ratifying and confirming all that such
attorney-in-fact, or his substitute or substitutes, shall lawfully do or
cause to be done by virtue of this Power of Attorney and the rights and
powers herein granted. The undersigned acknowledges that no such
attorney-in-fact, in serving in such capacity at the request of the
undersigned, is hereby assuming any of the undersigned?s responsibilities
to comply with Section 13 and Section 16 of the Securities Exchange Act
of 1934 and the rules thereunder, as amended.

       This Power of Attorney shall remain in full force and effect until
 revoked by the undersigned in a signed writing delivered to the foregoing
attorneys-in-fact.

       IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney
to be executed as of 8-7-2026.

       					/s/ Manher Joshi
					______________________
					Manher Joshi